EFFECTS OF NONPHARMACEUTICAL INTERVENTIONS DURING COVID-19 PANDEMIC ON PEDIATRIC ASTHMA EXACERBATIONS AND VIRAL INFECTIONS

Effects of nonpharmaceutical interventions during COVID-19 pandemic on pediatric asthma exacerbations and viral infections

Background: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in March 2020 led to the implementation of nonpharmaceutical interventions (NPIs) to curb its spread.Studies have shown that adult asthma exacerbations and viral infections decreased during NPI use.However, few studies have shown the effects of NPIs on pediatr

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Adipose Tissue-Derived Mesenchymal Stem Cells Induce Expansion of Interleukin-10-Producing Regulatory B Cells and Ameliorate Autoimmunity in a Murine Model of Systemic Lupus Erythematosus

Mesenchymal stem cells (MSCs) are multipotent cells characterized by immunomodulatory properties and are therefore considered a promising tool for the treatment of autoimmune diseases.One functional B-cell subset, regulatory B cells (Bregs), has recently been shown to restrain excessive inflammatory responses in autoimmune diseases.In the High Chai

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Mucosal vaccines for SARS-CoV-2: triumph of hope over experience

Summary: Currently approved COVID-19 vaccines administered parenterally induce robust systemic humoral and cellular responses.While highly effective against severe disease, there is reduced Laserdisc Parts effectiveness of these vaccines in preventing breakthrough infection and/or onward transmission, likely due to poor immunity elicited at the res

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